ADB-FUBINACA

 380,00 2200,00

The enantiomer of ADB-FUBINACA is claimed in Pfizer patent WO 2009/106982 and has been reported to be a a potent agonist of the CB1 receptor and CB2 receptor with a EC50 value of 1.2 nM and 3.5 nM respectively.
The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications

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Description

buy online ADB-FUBINACA

ADB-FUBINACA is a synthetic cannabinoid that has recently been identified in herbal blends.1 Its name refers to its structure, which has a 1-amino-3,3-dimethyl-1-oxobutan-2-yl (ADB) group linked to a 4-fluorobenzyl-1H-indazole-3-carboxamide (FUBINACA) base at the amide group. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.

What is ADB-FUBINACA ?  buy online ADB-FUBINACA

 Synthetic cannabinoid (SC) designer drugs based on indole and indazole scaffolds and featuring L-valinamide or L-tert-leucinamide side-chains are encountered with increasing frequency by forensic researchers and law enforcement, and are associated with serious adverse health effects. However, many of these novel SCs are unprecedented in the scientific literature at the time of their discovery, and little is known of their pharmacology. Here we report the synthesis and pharmacological characterization of AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, 5F-ADBICA, and several analogues. All synthesized SCs acted as high potency agonists of CB1 (EC50 = 0.24-21 nM) and CB2 (EC50 = 0.88-15 nM) receptors in a fluorometric assay of membrane potential, with 5F-ADB-PINACA showing the greatest potency at CB1 receptors
Important information about ADB-FUBINACA ?  buy online ADB-FUBINACA 

ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group. ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl

TECHNICAL INFORMATION  buy online ADB-FUBINACA 

Formal Name ​N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide​
CAS Number 1863065-92-2
Synonyms
  • ADB-CHMINACA
Molecular Formula C21H30N4O2
Formula Weight 370.5
Purity ≥98%
Formulation A neat solid
SMILES O=C(NC(C(N)=O)C(C)(C)C)C1=NN(CC2CCCCC2)C3=C1C=CC=C3
InChI Code InChI=1S/C21H30N4O2/c1-21(2,3)18(19(22)26)23-20(27)17-15-11-7-8-12-16(15)25(24-17)13-14-9-5-4-6-10-14/h7-8,11-12,14,18H,4-6,9-10,13H2,1-3H3,(H2,22,26)(H,23,27)
InChI Key ZWCCSIUBHCZKOY-UHFFFAOYSA-N

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ADB-FUBINACA

50g, 100g, 500g, 1kg

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